Acidification of the Urine and Bicarbonate Excretion Q1

Q-1. Which of the following is the principle buffer in interstitial fluid?
a) Carbonic acid
b) H2PO4
c) Histidine containing compounds
d) Other proteins

Answer: Carbonic acid
Explanation:
Principle buffers in body fluids:
Intra-cellular fluid- Carbonate and proteins systems
Interstitial fluid-Carbonate system
Blood- Hemoglobin, proteins and Carbonate systems
CSF and urine- Carbonate and Phosphate systems