Hyperprolactinemia causes
HIGH PROLACTINE
Hypothalamic and pituitary disease
Idiopathic
Granulomatous disease, e.g. sarcoidosis
Hypothyroidism (primary)
Physiological : pregnancy, nipple stimuli, stress, sleep, etc.
+Pituitary tumors: prolactinomas
Reserpine
+Renal failure (chronic)
Opiates and other drugs - metochlopramide, methyldopa, etc.
Lymphocytic hypophysitis
Adenomas secreting GH, ACTH, prolactine
Cirrhosis of liver
+Convulsion
Trauma to the chest wall
Irradiation (cranial)
Nelson’s syndrome
Estrogen