“Lung hamartoma”
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■ It is a relatively common lesion that is usually discovered as an incidental, rounded radio-opacity (coin lesion) on a routine chest film.
■ Most are, solitary, less than 3 to 4 cm in diameter, and well circumscribed.
■ Pulmonary hamartoma consists of nodules of connective tissue intersected by epithelial clefts.
■ Cartilage is the most common connective tissue, but there may also be cellular fibrous tissue and fat.
■ The epithelial clefts are lined by ciliated columnar epithelium or nonciliated epithelium and probably represent entrapment of respiratory epithelium.
■ The traditional term hamartoma is retained for this lesion, but it is in fact a clonal neoplasm associated with chromosomal aberrations involving either 6p21 or 12q14-q15…
