A 32-year-old man presents with unilateral gynaecomastia. He had breast reduction surgery on the other side 10 yrs ago. On examination he has, sparse body hair in the axilla and pubic regions. Two testicles are identified, both of small volume. On further questioning you elucidate that he has a normal sense of smell. His blood tests reveal:
Testoterone
4nmol/l (9-35)
LH + FSH
elevated
Prolactin
400mU/l (<360)
Which of the following is the most likely diagnosis?
Klinefelter’s syndrome
Kallman’s syndrome
Androgen insensitivity
Testicular feminisation
17-beta hydroxylase deficiency