Some important informative points
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Damage to nervous tissue is repaired by : Neuroglia
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Mycosis fungoides : Cutaneous lymphoma
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Secondary amyloidosis complicates: Chronic osteomyelitis
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The earliest feature of TB is: Lymphocytosis
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The low grade non-hodgkins lymphoma is : Follicular
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Liquefactive necrosis is seen in : Brain
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The crescent forming glomerulonephritis is: RPGN
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Earliest feature of correction of IDA is : Reticulocytosis
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Kupffer’s cells are found in : Liver
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Heart failure cells are found in : Lungs
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Psammoma bodies show: Dystrophic calcification
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Beta-microglobulin: is not a tumor marker
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Commonest benign tumor of liver : Hemangioma
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Blood when stored at 4 degree celcius can be kept for: 21 days
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Congo-red with amyloid produces: Brilliant pink colour
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Cloudy swelling does not occurs in : Lungs
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Gamma Gandy bodies contains hemosiderin and : Ca++
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Hutchinson’s secondaries in skull are due to tumors in : Adrenals
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Albumino -cytologic dissociation occurs in cases of: Guillain Barre syndrome
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Metastatic calcification is most often seen in : Lungs
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ASLO Titres are used in the diagnosis of: Acute rheumatic fever
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Apoptosis is inhibited by : bcl-2
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CEA: is not used as a tumor marker in testicular tumours
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Onion peel appearance of splenic capsule is seen in : SLE
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Lardaceous spleen is due to deposition of amyloid in : Sinusoids of red pulp
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Most common valve not involved in rheumatic fever: Tricuspid
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Antiglaidin antibodies are seen in : Celiac disease
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Focal diffuse gall bladder wall thickening with comet tail reverberation artifacts
on USG is in : Adenomyomatosis of gall bladder
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Organelle that plays a pivotal role in apoptosis : Golgi complex
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Sickle cell Red blood cells: Protective against adult malaria
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BRCA-l gene lies on chromosome: 17
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Common complement component for both intrinsic & extrinsic the pathways is :
C3
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Hypersensitivity vasculitis is seen in : Postcapillary venules
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Onion skin thickening of arteriolar wall is seen in: Hyperplastic arteriosclerosis
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The production of mature spermatozoa from spermatogonia takes 70 days.
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Testosterone is converted to dihydrotestosterone in the prostate.
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Sex hormone-binding globulin (SHBG) binds testosterone with a higher affinity
than estradiol.
- The production of estradiol by the testes requires Leydig cell, Sertoli cells, LH, and
FSH.
- Estradiol synthesis in the graafian follicle involves Stimulation of aromatase in
the granulosa cell by FSH.
- Granulosa cells do not produce estradiol from cholesterol because they do not
have an active 17α-Hydroxylase .
- A clinical sign indicating the onset of the menopause is an increase in plasma FSH
levels.
- Increased progesterone during the postovulatory period is associated with an
increase in basal body temperature by 0.5 to 1.0C.
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Nitric Oxide In GIT acts Primarily as Smooth Muscle relaxant.
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Sigmoid colon have maximum Post prandial contractibility.
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Acidity of chyme is the most important stimulus for the release of secretin from
duodenal mucosa.
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The most important stimulus for release of secretin is Amino acids.
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Short chain fatty acid produced by bacteria are maximally absorbed in Colon.
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Fat in duodenum results in Gall bladder contraction.
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Maximum absorption of water occurs in jejunum.
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Gastric secretions decreased by somatostatin.
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Calcium absorption in gut is increased in alkaline ph.
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“C” in CRP stands for the C- polysaccharide of Pneumococcus.
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Factor XIII helps in bridging the fibrin in a clot and stabilizing the clot.
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The life span of RBC is 120 days.
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Glycophorin is present in Erythrocyte.
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In hemopoiesis G-CSF and GM-CSF causes Granulocytosis.
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Cell type, which lacks HLA antigen, is Red blood cell.
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The function common to neutrophils, moncyte & macrophage is Phagocytosis.
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Enzyme responsible for respiratory burst is: Oxidase
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A major lipid of mitochondrial membrane is: Cardiolipin
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Alpha fetoprotein is genetically and structurally related to : Albumin
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In the mucosal cells, triglycerides are formed primarily in the : Golgi apparatus
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Biosynthesis of the enzyme pyruvate carboxylase is repressed by : Insulin
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Mucin dot test is done to detect: Hyaluronate in synovial fluid
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The cofactor required for the activity of sulfite oxidase is : Molybdenum
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The estimation of-methyl histidine in urine is used to study: Skeletal muscle mass
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The screening test for gestational diabetes mellitus that has the highest
sensitivity is : 50gm glucose challenge test
- Nephelometry is based on the principle of: Light attenuated in intensity by
scattering
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Vit. K is required for : Carboxylation
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Type -II collagen : is found in hyaline cartilage.
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Cation used in PCR is: Magnesium
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Poly (A) translates into: Polylysine
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Replacing alanine by Tryptophan will increase UV absorbance of protein at
280nm wavelength
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Biotin: is responsible for carboxylation reaction
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NO is synthesized by : Arginine
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Splicing is done by : Sn RNA
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Hyaluronic acid a mucopolysaccharide is present in : Vitreous humor
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In Maple syrup disease, the amino acids Not excreted in urine: Phenylalanine
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Zinc is required for: Alcohol dehydrogenase