Turner’s syndrome
-ovarian dysgenesis - present with primary amenorrhea, sexual infantilism, and short stature
-associated abnormalities - webbed neck, coarctation of the aorta (46XX), high-arched palate, cubitus valgus, broad shield-like chest with widely spaced nipples, low hairline on the neck, short metacarpal bones and renal anomalies
-high FSH and LH levels
-bilateral streaked gonads
-karyotype - 80% 45 XO; 20% mosaic forms (46XX/45XO)
-treatment - hormone replacement therapy (HRT)