What are the treatments for focal segmental glomerulosclerosis (FSGS)?

What are the treatments for focal segmental glomerulosclerosis (FSGS)?

Treatment for FSGS depends on the type and cause, your age, and whether you have other health conditions. Doctors aim to control symptoms to help you maintain a good quality of life and slow or prevent progressive scarring so that it does not lead to kidney failure.

In some people with secondary FSGS, treating the underlying condition may stop kidney damage from progressing. Doctors cannot repair glomeruli, but over time, kidney function may improve in these people.

Other treatments for FSGS include:

  • Angiotensin-converting enzyme (ACE) inhibitors: Drugs that treat high blood pressure.
  • Antibiotics: Medicines to treat infections.
  • Diuretics: Medications that lower blood pressure and ridding the body of excess fluids.
  • Immunosuppressive drugs: Drugs that manage the immune system response, such as cyclosporine and tacrolimus.
  • Plasmapheresis: A procedure that decreases the number of antibodies by removing plasma (liquid) from the blood.
  • Prednisone: A drug that lowers levels of protein in the urine.

What are the complications associated with focal segmental glomerulosclerosis (FSGS)?

FSGS can lead to high blood pressure and high cholesterol, and in some cases, FSGS can lead to kidney failure. This condition can be life-threatening and requires emergency medical treatment. Seek immediate care if you have FSGS and experience any of these symptoms of kidney failure:

  • Uncontrolled high blood pressure.
  • Nausea, vomiting or loss of appetite.
  • Swelling in the arms, legs or face.