A 12 year old boy presents with polyarthritis, subcutaneous nodules and purposeless, involuntary arm movements that started three days back. He had an episode of pharyngitis with fever four weeks ago not treated with antibiotics but now suspected to be of streptococcal etiology. Which of the following antigens is primarily invoked in this delayed presentation of disease?
- A. M protein
- B. Streptolysin O
- C. Streptolysin S
- D. Erythrogenic exotoxin A
- E. Streptococcal pyrogenic exotoxin A
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