42-year-old mildly overvveight man is being evaluated for his second episode of deep vein thrombosis in 2 years

42-year-old mildly overvveight man is being evaluated for his second episode of deep vein thrombosis in 2 years.

Both episodes appear to have been unprovoked. He has no recent prolonged immobility, long-distance travel, or

lower-extremity trauma. The patient has no past medical history of diabetes, cancer, or liver disease. A

thrombophilia workup is ordered. Use of which of the following drugs is most likely to lead to low protein S levels?

  • 0 A. Aspirin
  • 0 B. Clopidogrel
  • 0 C. Heparin
  • 0 D. Simvastatin
  • 0 E. Warfarin

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