55-year-old man comes to the physician with acute-ooset muscle pain. His other medical problems include hypertension,
hyperhpldemIa, and a myocardial mfarctIon 2 months ago. His medications include metoprolol, hsmopril, aspirin, and simvastalin. His
blood pressure IS 130/80 mm Hg and pulse is 60/min. Examination shows oo muscle weakness There IS no hepatosp!enomegaly
No skm rash ,s present Lrver function tests show slightly increased aspartate am1notransfarase and alanine aminotransferase The
serum crealIne lonase level rs elevated The physician suspects a drug-induced reaction Whteh of the following is the most likely
mechanism of action for this drug?
- Q A Immune-mediated reaction
- Q B Cell surface receptor blockage
- Q C Extracellular enzyme blockage
- QD inhibition of intracellular synthesis palhway
- Q E Damage of membrane-bound lipids
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