A 24 year old female presents with petechiae and has her spleen palpable till umbilicus

NEET PG
#1

A 24 year old female presents with petechiae and has her spleen palpable till umbilicus. The WBC count is found to be 85,000/cu.mm with immature white cells seen in peripheral blood smear. The diagnosis would be

(a) CML

(b) CLL

(c) AML

(d) ALL

The clinical presentation described is suggestive of acute leukemia, particularly acute myeloid leukemia (AML).

Key features pointing towards AML in this scenario include:

  1. Petechiae, which can result from thrombocytopenia due to bone marrow infiltration.
  2. Splenomegaly, which is common in AML and reflects extramedullary hematopoiesis.
  3. Elevated white blood cell (WBC) count, especially with immature white cells seen in the peripheral blood smear, indicating a leukemic process.

Therefore, the correct answer is (c) AML.