A 26-year-old female immigrant from Africa comes to the physician because of abdominal
pain. Her temperature is 38.7 °C (101.7 °F), with a heart rate of 82 bpm and a blood pressure
of 111/79 mmHg. She had taken chloroquine before arriving in the United States a week ago.
Physical examination shows a palpable mass in the left upper abdominal quadrant. A
peripheral blood smear is shown.
Mefloquine and primaquine are given and her symptoms improve. What is the most likely
causative organism?
- A. Plasmodium vivax
- B. Plasmodium ovale
- C. Plasmodium malariae
- D. Plasmodium falciparum
- E. Plasmodium knowlesi
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A 21-year-old woman comes to the physician complaining of an inability to move her arms
and legs. She was rushed to the hospital by emergency medical services 20 minutes ago
after cliff diving. She is alert, oriented, and does not require a ventilator. The spinal cord is
most likely severed at which vertebral level?
- A. C1
- B. C3
- C. C5
- D. C7
- E. T1
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An investigator is experimenting with the ability of drug X to increase heart rate. She
anesthetizes 100 mice that have denervated hearts. The drug is given intravenously at a
continuously increasing dose. Two dose-response curves are plotted.
What is the therapeutic index (TI) of drug X?
- A. ½
- B. 2
- C. 6
- D. 7
- E. 100
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