A tumor that originates in which of the following anatomic locations?

A 40-year-old woman with a history of diabetes complains of recent changes in her bodily appearance. A photograph of the patient is shown in the image. Laboratory studies reveal elevated serum corticosteroids and low serum corticotropin. Administration of dexamethasone does not lower serum levels of corticosteroids. This patient most likely has a tumor that originates in which of the following anatomic locations?

image

  1. Adrenal cortex, zona fasciculata
  2. Adrenal cortex, zona glomerulosa
  3. Adrenal cortex, zona reticularis
  4. Adrenal medulla
  5. Anterior pituitary