Q-91. Which of the following is not natural estrogen?
a) Mestranol
b) Ethinyl-estradiol
c) Ethyl estradol
d) Estriol
e) Estrone
Answer: a and b
Explanation:
Natural estrogens:
17 beta estradiol
Estrogen
Estriol
Synthetic steroidal estrogens:
Ethinyl-estradiol
Mestranol
Synthetic non-steroidal estrogens:
Diethylstilbestrol
Hexestrol
Q-92. Investigation helpful is making diagnosis of placenta praevia
a) TA-USG
b) Trans-perineal USG
c) TV USG
d) MRI
e) Double set exam
Answer: All
Explanation:
Q-93. Inhibin are secreted by
a) Granulosa cells tumor of the ovary
b) Endometrial stromal tumor
c) Endo-dermal sinus tumor
d) Endometrial adeno carcinoma
e) Adrenocortical tumor
Answer: Granulosa cells tumor of the ovary
Explanation:
Inhibin B is raised in Granulosa cells tumor of the ovary
Inhibin A is raised in Granulosa cells tumor of the ovary and epithelial mucinous type of tumor
Q-94. Not secreted by corpus luteum
a) Estradiol
b) Inhibin A
c) Progesterone
d) h-CG
e) h-PL
Answer: d and e
Explanation:
Hormones secreted by corpus luteum:
Progesterone
Estradiol
Inhibin A
Important point:
h-CG- Placenta and fetal kidney
h-PL (Human placental lactogen)- Trobhoblast
Q-95. Most common causes of maternal anemia in pregnancy
a) Acute blood loss
b) Iron deficiency state
c) GI blood loss
d) Hemolytic anemia
e) Thalassemia
Answer: a and b
Explanation:
Most common causes of maternal anemia in pregnancy:
Acute blood loss
Iron deficiency state
Common causes of maternal anemia in pregnancy:
Iron deficiency anemia
Acute blood loss
Megaloblastic anemia
Acquired hemolytic anemia
Aplastic or hypo-plastic anemia
Hereditary- Thalassemia, Sickle cell anemia and hereditary hemolytic anemia
Q-96. A 15x 15 cm ovarian cyst has been diagnosed in an 8 weeks pregnant lady. Further management includes
a) Only follow up without surgical intervention
b) Laparotomy at 14-16 weeks
c) Caesarean section and ovariotomy at term
d) Surgery after delivery
e) Immediate operation
Answer: Laparotomy at 14-16 weeks
Explanation:
Ovarian cyst:
Large size > 6-8 cm:
Surgical treatment
Best time for surgery:
Between 14-18 weeks
Q-97. Treatment of CA cervix stage I-b includes
a) Surgery
b) Chemotherapy
c) Radiotherapy
d) Cryotherapy
e) LEEP
Answer: a, b and c
Explanation:
Treatment of CA cervix:
Stage I-a 1:
Therapeutic conization or extra-fascial hysterectomy
Stage I-a 2:
Radical trachelectomy or radical hysterectomy
Stage I-b 1 and 2:
Radical trachelectomy or Type III radical hysterectomy with pelvic lymphadenectomy
Stage II-b-IV-a:
Radiation therapy (Traditionally) or
Chemotherapy and radiation therapy (Preferred now)
Stage III-b:
Chemotherapy and radiation therapy (Preferred now)
Q-98. Adenocarcinoma cervix is associated with
a) HPV 6
b) HPV 11
c) HPV 16
d) HPV 18
e) HPV 51
Answer: c, d and e
Explanation:
Human papilloma-viruses are DNA viruses that infect basal epithelial (skin or mucosal) cells.
There is high-risk genotypes, including genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 66, can lead to cervical cancer and are associated with other mucosal ano-genital and head and neck cancers.
Together, HPV 16 and 18 accounted for majority of adeno-carcinoma cervix.
Q-99. Drugs used for ovulation induction are
a) GnRH
b) Clomiphene citrate
c) Gonadotropins
d) Letrozole
e) Danazole
Answer: b and c
Explanation:
Drugs used for ovulation induction:
Clomiphene citrate
Gonadotropins injections in Hypo-gonadotropic Hypo-estrogenic Anovulation
Q-100. True about h-CG
a) α-subunit identical to LH, FSH &TSH
b) Causes involution of corpus luteum
c) Doubles in 7-10 days
d) Max level seen at 60-70 days of gestation
e) Detected in serum and urine 8-9 days after ovulation
Answer: a, d and e
Explanation:
Human Chorionic Gonadotropin (HCG):
Within 9 days after fertilization, the fertilized egg moves down the fallopian tube into the uterus and implants to the uterine wall.
Once the fertilized egg implants, the developing placental Syncytio-trophoblast begins releasing h-CG into your blood and max level seen at 60-70 days of gestation (Doubling time 1.4-2 days).
HCG may also be made abnormally by germ cell tumors.
HCG levels are often tested in a woman who may have a molar pregnancy, or chorio-carcinoma.
Important points:
Human Chorionic Gonadotropin is chemically and functionally similar to pituitary LH.
Alpha subunit is biochemically similar to LH, FSH and TSH.
Beta subunit is relatively unique to HCG.