All of the following organisms are known to survive intracellularly except

[Medicoman]

All of the following organisms are known to survive intracellularly except -

• 1. Neisseria meningitides
• 2. Salmonella typhi.
• 3. Streptococcus pyogenes
• 4. Legionella pneumophila

exp:

1. Facultative intracellular organisms

• Besides obligate intracellular organisms, some other organisms can live intracellularly → Facultative intracellular organisms.

• These bacteria also have capability of synthesis their own ATP, So they usually live extracellularly (in contrast obligate intracellular organisms).

• These bacteria are phagocytosed by the host’s macrophages and neutrophils yet survived within these WBCs by inhibiting phagosome - lysosome fusion, thus escaping host’s toxic H2O2 and superoxide radicals.

• Important examples :-

• Listeria monocytogenes - Yersinia - Brucella - Mycobacterium

• Neisseria - Salmonella typhi - Legionella - Francisella tularensis