Best screening test for acute hepatitis B infection ?
A.HBsAg and AntiHBs
B.HBsAg and Anti-HBc IgM
C.AntiHBe
D.HBeAg
E.HBcAg
Regarding Osteogenesis imperfecta
A. Lower bone density
B. Sensory deafness
C. Hypermobility
Nephrology:
A 35-year-old type 1 diabetic presented eight months following a renal transplant with fever, night sweats and malaise. He had experienced two episodes of transplant rejection, which were successfully reversed with corticosteroids. He was currently maintained on prednisolone and ciclosporin. On examination he had a temperature of 39°C (102.2°F). The heart rate was120 beats/min and blood pressure was 140/60 mmHg. The respiratory rate was 40/min. Precordial examination revealed an early diastolic murmur at the left lower sternal edge. The chest was clear. The abdomen including the graft was non-tender.
Investigations are shown.
Hb 10 g/dl, WCC 10×10^9/l,
Neutrophils 7×10^9/l, Lymphocytes 2.5×10^9/l, Eosinophils 0.04×10^9/l, Basophils 0.1×10^9/l, Monocytes 0.4×10^9/l, Platelets 300×10^9/l, ESR 100
Sodium130 mmol/l, Potassium 5.5 mmol/l, Chloride 87 mmol/l, Bicarbonate 22 mmol/l, Urea 9 mmol/l, Creatinine 130 mol/l
Glucose 6 mmol/l
Urine output 45 ml/hr
Urinary microscopy Red blood cells and no white cell casts
ECG Sinus tachycardia.
What is the most likely diagnosis?
a. Acute renal transplant rejection.
b. CMV infection.
c. Infective endocarditis.
d. Gram-negative sepsis.
e. Ciclosporin nephrotoxicity.
A 70-year-old male underwent coronary angiography after presenting with unstable angina. The angiogram revealed that three-vessel coronary artery disease resulting in deployment of stents in the left anterior descending and right coronary arteries. The following day hedeveloped general malaise and a fever.
On examination he had a vasculitic rash on his hands and feet. The patient had a past history of asthma. His medications included aspirin, clopidogrel, simvastatin andheparin.
Investigations are shown.
Hb15 g/dl, WCC11 109/l, Neutrophils 8 109/l, Lymphocytes 1.5 109/l, Eosinophils 1.5 109/l, Platelets 200 109/l, ESR 80 mm/h
CRP 100 g/l,
Urea 13 mmol/l, Creatinine 178 mol/l,
ANA Negative
ANCANegative
C3Low
C4Low
Blood culture Sterile
Urinalysis White cells ++ Protein ++
What is the most likely diagnosis?
a. Infective endocarditis.
b. Cholesterol atheroemboli.
c. Churg–Strauss syndrome.
d. Polyarteritis nodosa.
e. Contrast nephropathy.
1mg dexamethasone =
A.7 mg prenisolone
B. 10 mg prednisolone
C. 5 mg prednisolone
D. 20 mg prednisolone
E. 25mg prednisolone
HIV positive status is diagnosed on basis of a positive ELISA test, which becomes positive?
A 4-10 weeks after exposure
B immediately after exposure
C 2 -4 weeks after exposure
●Antileukotriens(montelukast)
useful in asprin induced asthma
●Muscarinic antagonist (ipratropium)
useful in BB induced asthma