Diabetic nephropathy is one of the most important complications of diabetes type-1 and type-2. Which of the following is the key investigation to exclude early diabetic nephropathy?
- A. Blood urea and creatinine
- B. Microalbuminuria
- C. Serum cholesterol
- D. Blood sugar level
- E. Renal biopsy
0 voters
Answer: Microalbuminuria
Description: Diabetic Nephropathy is the most common cause of End-stage renal disease (ESRD) and Microalbuminuria is the earliest clinical sign of diabetic nephropathy.
Microalbuminuria is an important risk factor for cardiovascular disease in type-2 diabetes
The natural history of diabetic nephropathy:
Hyperglycemia —-> ↑ GFR —-> Microaalbuminuria —-> Proteinuria —-> ↓GFR —-> ESRD (ENd stage renal disease)
Causes of Chronic kidney diseases:
- Diabetic Nephropathy ( Most Common cause )
- Hypertensive nephropathy
- Glomerulonephritis
- Polycystic kidney disease
- Urological