Example of allosteric inhibition
a) Inactivation of glycogen synthase by phosphorylation
b) Decreased synthesis of glucokinase by glucagon
c) Inhibition of PFK-1 by citrate
d) All of the above
Correct Answer - C
Answer-Ans. is ‘c’ i.e., Inhibition of PFK-l by citrate [lRef,
Dinesh puri 3d/e p. 1161 ]
Enzyme:-Phosphofructokinase I
Pathway:- Glycolysis
Stimulator:- AMP, ADP, fructose-6-phosphaie, fuctose-2,6-
bisphophate.
Inhibitor:- ATP, citrate, Ca2+, Mg+