How fever is beneficial?

NEET SS
#1
  1. How fever is beneficial?
    1. Leukocytes show maximum phagocytic activity between
  • 38-40°C
    1. During fever the circulating iron level goes down. Iron is
  • helpful for the growth and reproduction of bacteria. So,
  • when circulating iron level goes down, bacterial growth is
  • prevented
    1. Fever produces direct inhibiting effect on certain viruses
  • like polio and coxsackie viruses.

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  1. How fever causes weight reduction?
    1.  BMR
    1.  protein breakdown (catabolism)
    1. Water loss
    1. Anorexia (loss of appetite)

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  1. Fever blisters (Herpes simplex) seen in
    1. Pneumonia
    1. Malaria
    1. Streptococcal infections
    1. Meningococcal infections

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  1. Rickettsial fever
    Rare in
    1. Typhoid
    1. TB
    1. Smallpox
    1. Mycoplasma pneumoniae

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  1. Beneficial effects of fever
    1. Neurosyphilis
    1. Some forms of chronic arthritis
    1. Gonorrhea
    1. Malignancy—In fever there is release of endogenous
  • pyrogens which activate T cells and this enhances host
  • defense mechanism.

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  1. Ill effects of fever
    1. Epileptiform fits
    1. Weight loss
    1. Sweating causes salt and water depletion
    1. Depletion – Dehydration – Delirium

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  1. Fever without infection
    1. Pontine hemorrhage
    1. Factitious fever
    1. Habitual hyperthermia
    1. Drugs – Atropine, etc.
    1. Malignancy – Leukemia, Hodgkin, etc.
    1. Rheumatological disorders, e.g. SLE, rheumatoid arthritis,
  • etc.

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  1. Fever in cardiovascular system disorders
    1. Rheumatic fever
    1. Infective endocarditis
    1. Atrial myxoma
    1. (TB) pericarditis (effusion)
    1. Polyarteritis nodosa
    1. Myocardial infarction
    1. Pulmonary thromboembolism
    1. CCF
    1. Temporal arteritis

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  1. Fever in respiratory system disorders
    1. Pyogenic infectious of lung – suppurative
    1. Bronchitis
    1. Pneumoconiosis
    1. Pneumonia
    1. Pleurasy

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  1. Fever in gastrointestinal tract disorders (abdominal)
    1. TB peritonitis and TB abdomen
    1. Crohn’s disease
    1. Acute appendicitis
    1. Subdiaphragmatic abscess
    1. Perinephric abscess

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  1. Fever in liver disorders
    1. Infective hepatitis – preicteric stage
    1. Amoebic liver abscess
    1. Malignancy
    1. Cholecystitis

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