In an inflammatory response, macrophages are usually derived from -

In an inflammatory response, macrophages are usually derived from -

    1. Monocytes
    1. Reticuloendothelial cells
    1. Neutrophils
    1. Lymphocytes

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Monocytes and monoculear phagocytes

  • Mononuclear phagocytes (MP) also known as macrophages or histiocytes are distributed throughout virtual all tissues.

  • The macrophage is the dominant cellular player in chronic inflammation.

  • MP arise from monoblast in the marrow, and they are released into the circulation as monocytes.

  • The monocytes then migrate to tissues and become part of the tissue (fixed) macrophages.