In NEC there is vomiting also so sir why not metbolic alkalosis

In NEC there is vomiting also so sir why not metbolic alkalosis
Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease that can affect premature infants. NEC is characterized by inflammation and necrosis of the intestinal mucosa, which can lead to bowel perforation, sepsis, and other complications. Vomiting is a common symptom of NEC, along with abdominal distension, feeding intolerance, and bloody stools.

In terms of acid-base disturbances, NEC is more commonly associated with metabolic acidosis rather than metabolic alkalosis. This is because the underlying pathophysiology of NEC involves inflammation and ischemia of the intestinal mucosa, which can lead to tissue hypoxia and anaerobic metabolism. This, in turn, can result in the production of lactic acid and other organic acids, leading to metabolic acidosis.

The vomiting associated with NEC can lead to a loss of gastric acid and chloride, which could theoretically cause metabolic alkalosis. However, this is generally not a prominent feature of NEC. In fact, vomiting in the setting of NEC is often associated with a loss of bicarbonate, which can exacerbate the metabolic acidosis.

Overall, the acid-base disturbances in NEC are complex and multifactorial, and may involve a combination of metabolic acidosis, respiratory acidosis, and metabolic alkalosis depending on the severity and duration of the disease. However, metabolic acidosis is generally the more common acid-base disturbance seen in NEC.