A lacrosse player develops athlete’s foot (tinea pedis). A drug with which the following mechanisms would be most effective for this patient?
Binding to hemagluttinin
Blockade of mycolic acid incorporation into cell wall
Inhibition of ergosterol synthesis
Inhibition of reverse transcriptase
Inhibition of transcription
Correct answer
Inhibition of ergosterol synthesis
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correct answer: C
Tinea pedis is a fungus and therefore does not have mycolic acids (B), reverse transcriptase (D), or hemagluttinin (A). A transcription inhibitor (E) would also affect the patient’s normal cells, resulting in terrible side effects. Therefore, inhibition of ergosterol synthesis
is the most effective therapy.