New drugs for dyslipidemia:

NEET PG Pharmacology
#1

New drugs for dyslipidemia:

  1. Icosapent - Ethylester of eicosapentaenoic acid, Decreases VLDL-TG, As an adjunct to diet in severe hypertriglyceridemia

  2. Lomitapide - Inhibits microsomal triglyceride transfer protein, decreases VLDL, chylomicrons synthesis

  3. Alirocumab, Evolocumab - Proprotein convertase subtilisin kexin type 9 (PCSK-9) inhibitor. Blocks degradation of LDL-R, Decreases blood LDL

  4. Bempedoic acid - Inhibits ATP citrate lyase. decreases synthesis of LDL.