Online Test Series 36

MCQs PG Medical Entrance Mock Tests
#1
  1. Question

True statement regarding platelet function defects?

1. Increased platelet count with increased bleeding time
2. Decreased platelet count with increased bleeding time
3. Normal platelet count with increased bleeding time
4. Normal platelet count with normal bleeding time
  1. Question

HbH is seen in which of the following conditions?

1. Deletion of 4 alpha genes
2. Deletion of 4 beta genes
3. Deletion of 3 beta genes
4. Deletion of 3 alpha genes
  1. Question

Most commonly seen antibody in antiphospholipid antibody syndrome?

1. Anti beta 2 glycoprotein antibody
2. Anti centromere antibody
3. Anti nuclear antibody
4. Beta 2 microglobulin antibody
  1. Question

False regarding Bernard Soulier Syndrome?

1. Decreased platelet count
2. Ristocetin aggregation normal
3. Platelet aggregation in response to collagen and ADP is normal
4. Large platelets
  1. Question

All are true about Xanthogranulomatous inflammation except?

1. Foam cells are present
2. Associated with tuberculosis
3. Multi-nucleated giant cells are present
4. Yellow nodules are present
  1. Question

Which of the following is most characteristic feature of acute inflammation?

1. Vasodilatation and increased vascular permeability
2. Margination of leukocytes
3. Vascular stasis
4. Vasoconstriction
  1. Question

Which of the following enzymes are responsible for generating ‘oxygen burst’ within neutrophils for killing intracellular bacteria?

1. Glutathione peroxidase
2. Oxidase
3. Superoxide dismutase
4. Catalase
  1. Question

All of the following enzymes may contribute in generating free oxygen radicals within neutrophils for killing intracellular bacteria except?

1. NADPH oxidase
2. Superoxide dismutase
3. Glutathione peroxidase
4. Fenton’s reaction
  1. Question

Mineralocorticoid Receptors are found in all of the following, Except?

1. Colon
2. Liver
3. Hippocampus
4. Kidney
  1. Question

All are true about coagulation pathway except?

1. Calcium is necessary for several steps of coagulation pathway
2. Extrinsic pathway activation is via contact negatively charged surfaces
3. Factor X is important in both extrinsic and intrinsic pathway
4. Intrinsic pathway can be activated in vitro
  1. Question

Which of the following organelles plays a pivotal role in Apoptosis?

1. Mitochondria
2. Golgi Apparatus
3. Endoplasmic Reticulum
4. Nucleus
  1. Question

Alkalinization of urine is done during administration of which of the following chemotherapeutic drugs?

1. Cisplatin
2. Methotrexate
3. Ifosfamide
4. Ara-C (Cytarabine)
  1. Question

All of the following are known adverse effects of thalidomide, except:

1. Teratogenicity
2. Diarrhoea
3. Deep Vein Thrombosis
4. Peripheral Neuropathy
  1. Question

All of the following statements about Aprepitant are true except?

1. Agonist at Neurokinin receptor (NK1)
2. Crosses blood brain barrier
3. Ameliorates nausea and vomiting of chemotherapy
4. Metabolised by CYP3A4 pathway
  1. Question

Which of the following antihypertensive drugs should not be used in a patient on Lithium in order to prevent Lithium Toxicity?

1. Beta blockers
2. Clonidine
3. Calcium Channel Blockers
4. Diuretics
  1. Question

All of the following statements about Selective Estrogen Receptor Downregulator (SERD), Fulvestrant are true, Except

1. It is a selective estrogen antagonist
2. Used in the treatment of breast cancer
3. May be administered as ‘once a month’ dose
4. Slower acting, safer and less effective than SERM
  1. Question

Which of the following agents is used for the treatment of Thrombocytopenia secondary to myelosuppressive cancer chemotherapy?

1. Oprelvekin
2. Sargramostim
3. Erythropoietin
4. Filgrastim
  1. Question

All of the following statements about meglitinides are true, except:

1. Act by stimulating insulin release
2. Decrease Postprandial Hyperglycemia
3. Hypoglycemia is less common than with sulfonylureas
4. Act by decreasing insulin resistance
  1. Question

All of the following statements about Ranolazine are true, except:

1. Piperazine derived antianginal agent
2. Hypotension is an established adverse effect
3. May be used as first line agent in chronic angina
4. May improve Glycemic control
  1. Question

All of the following statement s about ‘Erlotinib’ are true except?

1. Food decreases its absorption
2. Tyrosine kinase inhibitor
3. Rashes may occur
4. Used in non small cell lung carcinoma