- Question
A patient of peptic ulcer was prescribed ranitidine and sucralfate in the morning hours. Why is this combination incorrect:
1. Ranitidine combines with sucralfate and prevents its action
2. Combination of these two drugs produces serious side effects like agranulacytosis
3. Ranitidine decreases the gastric pH so sucralfate is not able to act
4. Sucralfate inhibits absorption of ranitidine
- Question
Epstein Barr (EB) virus has been implicated in the following malignancies except:
1. Multiple myeloma
2. Nasopharyngeal carcinoma
3. Non Hodgkin‘s lymphoma
4. Hodgkin‘s disease
- Question
Among the following, all are hydrophilic hormones that act on cytosolic receptors except one which is a lipophilic hormone that acts on nuclear receptor?
1. Epinephrine
2. Thyroxine
3. ACTH
4. Growth hormone
- Question
False about pneumococcus is?
1. Meningitis caused by it is milder than by other organisms
2. Capsule aids in virulence
3. Commonest cause of otitis media and pneumonia
4. Bile sensitive
- Question
A young pregnant woman presents with fulminant hepatic failure. The most likely aetiological agent is:
1. Hepatitis E virus
2. Hepatitis C virus
3. Hepatitis A virus
4. Hepatitis B virus
- Question
Ova albumin antigen was injected into a rabbit. What is the first antibody produced against it?
1. IgM
2. IgG
3. IgE
4. IgD
- Question
Sympathomimetic drugs are useful in the therapy of all of the following conditions except?
1. Hypertension
2. Acute decompensated heart failure
3. Erectile dysfunction
4. Hypotension
- Question
Denominator in Maternal Mortality Rate?
1. Total number of married women
2. Total number of live births
3. Total number of births
4. Midyear population
- Question
A 60 year old man with rheumatic mitral stenosis with atrial fibrillation is on therapy for a fast ventricular rate. While on treatment, he developed a regular pulse of 64/min. The most likely drug being administered was:
1. Carvedilol
2. Verapamil
3. Digoxin
4. Propranolol
- Question
Which of the following is not an adverse effect of chronic amiodarone therapy?
1. Pulmonary fibrosis
2. Hypothyroidism
3. Hyperthyroidism
4. Systemic lupus erythematosus
- Question
All of the following statements are true regarding poliovirus except :
1. Asymptomatic infections are common in children
2. It is transmitted by feco-oral route
3. Live attenuated vaccine produces herd immunity
4. There is a single serotype causing infection
- Question
All of the following clinical features are associated with Enteroviruses except :
1. Herpangina
2. Myocarditis
3. Hemorrhagic fever
4. Pleurodynia
- Question
Laboratory diagnosis of viral respiratory tract infections can be established by all of the following tests except :
1. Isolation of viruses using centrifugation enchanced culture
2. Detection of virus specific IgM antibodies in single serum specimen
3. Detection of viral heamagglutination inhibiting (HAI) antibodies in a single serum specimen
4. Demonstration of viral antigens by indirect immunofluorescence assay in nasopharyngeal washings
- Question
Drug implicated for prolonging QT interval in a premature baby is :
1. Metoclopramide
2. Domperidone
3. Cisapride
4. Omeprazole
- Question
All the following statements regarding interactions of levodopa are correct except:
1. Pyridoxine reduces effect of levodopa in parkinsonism
2. In Parkinsonism, phenothiazines reduce its efficacy
3. It is a prodrug
4. Domperidone blocks levodopa induced emesis and its therapeutic potential
- Question
In which of the following phases of clinical trial of drug, ethical clearance is not required?
1. Phase II
2. Phase I
3. Phase III
4. Phase IV
- Question
All of the following Anticancer agents cause bone marrow depression except?
1. Chlorambucil
2. Daunorubicin
3. Flutamide
4. Doxorubicin
- Question
Carpal tunnel syndrome is caused by all except?
1. Amyloidosis
2. Hypothyroidism
3. Diabetes mellitus
4. Addison’s disease
- Question
All are true about pheochromocytoma except?
1. 90% are malignant
2. 95% occur in the abdomen
3. They secrete catecholamines
4. They arise from sympathetic ganglions
- Question
A highly ionized drug :
1. Crosses the placental barrier easily
2. Is excreted mainly by the kidneys
3. Is well absorbed from the intestine
4. Is highly protein bound
- Question
Which among the following is a cardioprotective fatty acid?
1. Palmitic acid
2. Stearic acid
3. Omega-3 fatty acids
4. Oleic acid
- Question
All of the following statements about an alpha-glucosidase inhibitor are true except:
1. Effective in both type l & 2 diabetes
2. Reduces intestinal absorbtion of carbohydrates
3. Hypoglycemia is a common & serious side effect
4. Can be used with other oral Hypoglycemic drugs
- Question
Which is not an autoimmune disease?
1. Grave’s disease
2. SLE
3. Myasthenia gravis
4. Sickle cell disease
- Question
All of the following are advantages of using Raloxifene over estrogen in post menopasual women except?
1. Reduces fracture rates
2. Avoids Endometrial hyperplasia
3. Reduces incidence of venous thrombosis
4. No increase in incidence of breast carcinomas
- Question
Methotrexate is used in all except:
1. Rheumatoid arthritis
2. Ankylosing spondylitis
3. Psoriasis
4. Sickle cell anemia
- Question
Which of the following does not bind to GABA receptor chloride channels?
1. Ethanol
2. Zolpidem
3. Alfaxalone
4. Buspirone
- Question
Auto-Rikshaw ran over a child’s thigh, there is a mark of the tyre tracks, it is an
1. Patterned bruise
2. Ectopic bruise
3. Imprint abrasion
4. Contact bruise
- Question
Vitamin K is involved in the post translational modification of?
1. Lysine
2. Glutamate
3. Aspartate
4. Proline
- Question
Which of the following statements is true regarding ARBO viruses :
1. Kyasanur Forest disease (KFD) is transmitted by ticks
2. Yellow fever is endemic in India
3. Dengue virus has only one serotype
4. Mosquito of culex vishnui complex is the vector of Dengue fever
- Question
Which one of the following statements about biguanides is not true?
1. Decrease hepatic glucose production
2. Don’t stimulate insulin Releas
3. Renal Dysfunction is not a contraindication for their use
4. Can be combined with sulfonylureas