Opioid tolerance develops to all of the following actions

Which of the following drug is most commonly used world wide in maintenance doses for opioid dependence
a) Naltrexane
b) Methadone
c) Imipramine
d) Disulfiram

All of the following statements about serotonin syndrome are true, except:
a) It is not an idiosyncratic reaction
b) Can be caused by SSRI
c) Dantrolene is the drug of choice
d) Associated with hyperthermia and hypertension

All of the following statements about Epidural opioids are true, Except
a) Acts on the dorsal horn substantia gelatinosa
b) May cause pruiritis
c) May cause Respiratory Depression
d) Gastrointestinal adverse effects are not seen

Opioid tolerance develops to all of the following actions, Except:
a) Miosis
b) Analgesia
c) Euphoria
d) Nausea and Vomiting