Resting membrane potential of nerve is equal to equilibrium potential

Resting membrane potential of nerve is equal to equilibrium potential of

    1. Na+
    1. Cl-
    1. K+
    1. HCO3-

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EXP:

Isoelectric potential of Cl- is -70mV and of K+ is -90mV.

According to ‘Ganong’ and ‘Principles of Medical Physiology’, the actual measured RMP of a nerve fibre is -70mV rather than the calculated value of -90mV. So in nerve fibers, the RMP is equal to or closer to the isoelectric potential of Cl-.

Whereas in muscle cells, the RMP is -90mV, which is equal to isoelectric potential of K+.