Rossmann fold is a super secondary structure or domain

Rossmann fold is a super secondary structure or domain ( area where one of the coenzyme can bind ) of protein which is alternating beta alpha beta fold .

It is commonly found in enzymes which use FAD, SAM, NAD, NADP.

Mostly these are dehydrogenases. This fold is conserved during evolution.

Examples of such enzymes:

Lactate dehydrogenase

Alcohol dehydrogenase

glyceraldehyde-3-P dehydrogenase

Malate dehydrogenase

Quinone oxidoreductase

6-phospho gluconate dehydrogenase

D- glycerate dehydrogenase

Formats dehydrogenase

3 alpha, 20 beta hydroxy steroid dehydrogenase