1.The concentration of O2 in adequate anaesthesia is –
2.Oxygen content in anaesthetic mixture is –
3.Not intravenous Anaesthetic agent –
(Ketamine, thiopentone, etomidate are intravenous anaesthetic agents. Cyclopropane is an inhalational (volatile) anaesthetic agent.)
4.All are true about propofol except –
1.Pleasant sedation & recovery
2.Safe in porphyria
4.Suppression of airway reflexes
(Porpofol has myocardial depressant action. Only IV inducing agent with cardiac stimulant action is ketamine.
Propofol has smooth & pleasant induction and recovery is rapid. Propofol has antiemetic effect and is safe in porphyria.
Propofol causes relaxation of laryngeal muscles, depression of laryngeal reflexes and there is no irritation of respiratory tract. Therefore, propofol is the intravenous anaesthetic agent of choice for intubation.)
5.True about propofol –
a) Indicated in egg allergy
b) Can be used in porphyria
c) It is of barbiturate group
d) Used in day care surgery
(Propofol is di-isopropylphenol (not a barbiturate).
Allergic reaction can occur in individuals having allergy to egg lecithin.
Propofol is safe in porphyria.
It is the intravenous anaesthetic of choice for induction in day care surgery.)
6.% of thiopentone–used in induction –
(Thiopentone is used in 2.5% concentration with a dose of 3-6 mg/kg.)
7.Dose of thiopentone used for induction is –
8.Intra arterial injection of thiopentone causes –
3.Necrosis of vessel wall
(Inadverent intra-arterial injection causes local vasoconstriction (vasospasm) and thrombosis which can cause ischemia and gangrene of the limb.
Note-IV injection cause generalized venodilatation due to which there is pooling of blood & hypotension. On the other hand intra-arterial injection results in localized vasospasm of the involved artery.)
9.Intravenous thiopentone pentox, produces –
e) Muscular excitation (locally)
Inadverent injection of thiopentone is painful and it causes vasodilatation (not vasospasm) which results in hypotension.
Thiopentone can cause mild muscular excitatory movements such as tremer, twitching, cough, hiccup.
Rash may occur due to hypersensitivity.
10.All are true about thiopentone except –
1.NaHCO3 is a preervative
2.Contraindicated in porphyria
3.Agent of choice in shock
4.Has cerebroprotective action
(Thiopentone causes hypotension → contraindicated in shock & hypotensive states.)