A patient with malignant lymphoma is treated with a chemotherapeutic agent that results in nuclear and cytoplasmic fragmentation of individual cells. Which of the following mechanisms is the most likely cause of the cellular fragmentation?
Acute inflammation
Apoptosis
Autophagy
Mitochondrial poisoning
Necrosis
Correct answer
Apoptosis
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correct answer: B
Apoptosis is the process that is described here. Along with cellular fragmentation, DNA laddering and cytochrome c release are also seen.
The other choices do not result in cell fragmentation.