Q 89. A highly ionized drug:
A. Is excreted mainly by the kidney.
B. Can cross the placental barrier easily.
C. Is well absorbed from the intestine.
D. Accumulates in the cellular lipids
Ans. A
Q 90. Which one of the following drugs is ‘topoisomerase 1 inhibitor’?
A. Doxorubicin.
B. Irinotecan.
C. Etoposide.
D. Vincristine.
Ans. B
Q 91. The following drugs have significant drug interaction with digoxin,
except:
A. Cholestyramine.
B. Thiazide diuretics.
C. Quinidine.
D. Amlodipine.
Ans. D
Q 92. One of the following is not true about nesiritide:
A. It is a brain natriuretic peptide analogue.
B. It is used in acutely decompensated heart failure.
C. It has significant oral absorption.
D. It has a short half-life.
Ans. C
Q 93. Antipsychotic drug-induced parkinsonism is treated by:
A. Anticholinergics.
B. Levodopa.
C. Selegiline.
D. Amantadine.
Ans. A
Q 94. Which one of the following is used in therapy of toxoplasmosis?
A. Artensenuate.
B. Thiacetazone.
C. Ciprofloxacin.
D. Pyrimethamine.
Ans. D
Q 95. The following statements regarding finasteride are true except:
A. It is used in the medical treatment of benign prostatic hypertrophy (BPH)
B. Impotence is well documented after its use.
C. It blocks the conversion of dihydrotestosterone to testosterone.
D. It is a 5-a reductase inhibitor.
Ans. C
Q 96. Eternacept acts by one of the following mechanisms:
A. By blocking tumor necorosis factor.
B. By blocking bradykinin synthesis.
C. By inhibiting cyclo-oxygenase-2.
D. By blocking lipoxygenase.
Ans. A
Q 97. In unconjugated hyperbilirubinemia, the risk of kernicterus increases with
the use of:
A. Ceftriaxone.
B. Phenobarbitone.
C. Ampicillin.
D. Sulphonamide.
Ans. D
Q 98. All of the following are topically used sulphonamides except:
A. Sulphacetamide.
B. Sulphadiazine.
C. Silver sulphadiazine.
D. Mafenide.
Ans. B
Q 99. Oculogyric crisis is know to be produced by all of the following drugs
except:
A. Trifluoperazine.
B. Atropine.
C. Perchlorperazine.
D. Perphenazine.
Ans. B
Q 100. Which of the following drugs is useful in prophylaxis of migraine?
A. Proproanolol.
B. Sumatriptan.
C. Domperidone.
D. Ergotamine.
Ans. A
Q 101. Inverse agonist of benzodiazepine receptor is:
A. Phenobarbitone.
B. Flumazenil.
C. Beta-Carboline.
D. Gabapentin.
Ans. C
Q 102. The group of antibiotics which possess additional anti-inflammatory and
immunomodulatory activities is:
A. Tetracyclines.
B. Polypeptide antibiotics.
C. Fluoroquinolones.
D. Macrolides.
Ans. D
Q 103. With which of the following theophylline has an antagonistic interaction?
A. Histamine receptors.
B. Bradykinin receptors.
C. Adenosine receptors.
D. Imidazoline receptors.
Ans. C
Q 104. One of the following is not penicillinase susceptible:
A. Amoxicillin.
B. Penicillin G.
C. Piperacillin.
D. Cloxacillin.
Ans. D
Q 105. Which one of the following is best associated with lumefantrine?
A. Antimycobacterial.
B. Antifungal
C. Antimalarial.
D. Antiamoebic.
Ans. C
Q 106. Which one of the following drugs increases gastro-intestinal motility?
A. Glycopyrrolate.
B. Atropine.
C. Neostigmine.
D. Fentanyl.
Ans. C
Q 107. Nevirapine is a:
A. Protease inhibitor.
B. Nucleoside reverse transcriptase inhibitor.
C. Non-nucleoside reverse transcriptase inhibitor.
D. Fusion inhibitor.
Ans. C