The primary direct stimulus for excitation of central chemoreceptors regulating ventilation is

The primary direct stimulus for excitation of central chemoreceptors regulating ventilation is

  1. Increased H+

  2. Increased CO2

  3. Increased O2

  4. Decreased CO2

Explanation:

The primary direct stimulus for excitation of central chemoreceptors regulating ventilation is H+ concentration in CSF and brain interstitium.