Treatment of impending perforation→ Keratoplasty

Keratoplasty, also known as corneal transplantation, can indeed be a treatment option for impending corneal perforation in certain cases. Impending corneal perforation refers to a situation where there is a high risk that the cornea, the clear outer layer of the eye, may rupture or develop a hole. This can occur due to various factors such as severe infection, trauma, corneal ulceration, or underlying corneal thinning disorders.

When conservative measures such as antibiotic therapy, lubrication, or patching fail to stabilize the cornea and prevent perforation, surgical intervention may be necessary. Keratoplasty involves replacing the damaged or diseased corneal tissue with healthy donor tissue obtained from a deceased individual.

There are different types of keratoplasty procedures, including:

  1. Penetrating Keratoplasty (PKP): This involves replacing the entire thickness of the cornea with donor tissue. PKP is typically performed for cases of advanced corneal disease or when the entire cornea is affected.
  2. Deep Anterior Lamellar Keratoplasty (DALK): DALK involves removing and replacing only the anterior layers of the cornea while preserving the innermost layer, known as the endothelium. DALK is often preferred in cases where the inner layers of the cornea are healthy, such as in keratoconus or certain corneal dystrophies.
  3. Descemet’s Stripping Endothelial Keratoplasty (DSEK) and Descemet’s Membrane Endothelial Keratoplasty (DMEK): These procedures specifically target the endothelial layer of the cornea, which is responsible for maintaining corneal transparency. DSEK and DMEK are typically performed in cases of corneal endothelial dysfunction, such as Fuchs’ endothelial dystrophy.

The choice of keratoplasty procedure depends on various factors, including the underlying cause of corneal pathology, the extent of corneal thinning or damage, and the surgeon’s expertise. In cases of impending corneal perforation, prompt surgical intervention with keratoplasty may be necessary to prevent vision-threatening complications such as intraocular infection or loss of eye integrity.

It’s important for individuals facing impending corneal perforation to consult with an ophthalmologist who can assess their condition and determine the most appropriate treatment approach, which may include keratoplasty or other interventions.