What is Glove and Stocking Hypostasis ?
Glove and stocking hypostasis, also known as glove and stocking neuropathy or distal symmetrical sensory neuropathy, refers to a pattern of sensory loss or altered sensation that primarily affects the hands (glove distribution) and feet (stocking distribution). It is a term used to describe a specific type of peripheral neuropathy characterized by a symmetrical involvement of the peripheral nerves.
In glove and stocking hypostasis, the sensory impairment typically starts at the extremities and progresses gradually towards the proximal parts of the limbs. It often presents as a loss of sensation, numbness, tingling, or a “pins and needles” sensation. The affected individuals may also experience a reduced ability to perceive temperature or pain.
This condition is commonly seen in peripheral neuropathies associated with various underlying causes, including:
- Diabetes mellitus: High blood sugar levels in diabetes can lead to nerve damage, causing peripheral neuropathy. Distal symmetrical sensory neuropathy is a common manifestation of diabetic neuropathy.
- Vitamin deficiencies: Deficiencies in vitamins such as vitamin B12, vitamin B1 (thiamine), and vitamin E can cause peripheral neuropathy, including the glove and stocking pattern.
- Alcohol abuse: Chronic alcohol abuse can lead to peripheral neuropathy, and the glove and stocking distribution is often observed in these cases.
- Certain medications: Some medications, such as certain chemotherapy drugs, can cause peripheral neuropathy with a glove and stocking distribution.
- Autoimmune disorders: Conditions like Guillain-Barré syndrome, systemic lupus erythematosus, and rheumatoid arthritis can involve peripheral nerves and cause the glove and stocking pattern of sensory impairment.
It is important to identify and address the underlying cause of glove and stocking hypostasis to manage the condition effectively. Treatment may involve managing the underlying condition, addressing any nutritional deficiencies, controlling blood sugar levels in diabetes, avoiding alcohol consumption, and providing symptomatic relief through medications to manage pain or discomfort.
If you or someone you know is experiencing symptoms suggestive of glove and stocking hypostasis, it is important to consult a healthcare professional for a proper evaluation and diagnosis. They can conduct a thorough examination, order relevant tests, and provide appropriate management strategies based on the underlying cause and individual circumstances.