What is primary immunodificiency disease
Primary immunodeficiency disease (PIDD) is a group of inherited disorders that affect the immune system. People with PIDD are born with a defective or absent immune system, which makes them more susceptible to infections and other health problems. There are over 300 different types of PIDD, each with its own specific symptoms and characteristics.
Common symptoms of PIDD include:
- Recurrent infections: People with PIDD are prone to frequent and severe infections, such as pneumonia, bronchitis, sinusitis, and skin infections.
- Delayed growth and development: Children with PIDD may experience delayed growth and developmental milestones.
- Autoimmune disorders: Some people with PIDD may develop autoimmune disorders, such as arthritis or lupus, where the immune system attacks the body’s own tissues.
- Inflammatory disorders: PIDD may also be associated with inflammatory disorders, such as Crohn’s disease or ulcerative colitis.
- Cancer: People with PIDD have an increased risk of developing certain types of cancer, such as lymphoma or leukemia.
PIDD is diagnosed through a combination of medical history, physical examination, and laboratory tests, including blood tests and genetic testing. Treatment may involve medications, such as antibiotics and immunoglobulin therapy, to boost the immune system and prevent infections. People with PIDD may also require close monitoring and ongoing management by a team of healthcare providers