Which of the following drug for the treatment of multiple sclerosis required 6 hr of ECG monitoring if used for first time:

NEET PG
#1

which of the following drug for the treatment of multiple sclerosis required 6 hr of ECG monitoring if used for first time -

  1. Natalizumab

  2. Fingolimod

  3. Glatiramer acetate

  4. Mitoxantrone

2 fingolimod because it causes bradycardia

Correct ans - 2 ( fingolimod ) bcz it can lead to 1 & 2 degree heart block & bradycardia … A 6-h period of observation (including electrocardiogram monitoring) is recommended for all patients receiving their first dose, and individuals with preexisting cardiac disease should probably not be treated with this agent !!